Derived from Peruvian Uña de Gato (Uncaria tomentosa) bark grown in the Amazon Rain Forest, AC-11® Carboxy-Alkyl-Esters (CAE's) are breakthrough new phytocompounds that support the natural DNA repair process. In the early 1990's, a research team from the University of Lund in Sweden began exploring the power of these compounds by spending time with the Ashaninka Indians in the Amazon Basin of Peru. There, they observed how the local medicine men prepared hot-water extracts of Uncaria tomentosa and how these extracts produced observable healing results. The team returned to Sweden to analyze the extract and spent more than two years identifying key compounds that demonstrated increased DNA repair in humans. Based on this youth re-activation discovery, a usage and composition patent was awarded: patent # 6,361,804. Nuvcare Health Sciences Inc. has licenced AC-11® for an anti-aging pill that increases DNA Repair, improves lean body composition, and improves skin surface health.

Derived from the Japanese Crimson Beauty Root (AKA.. Japanese Knotwood), Acti-Sirtuin™ Trans-Resveratrol (found only in NuvoCELL™) is responsible for activation of Sirtuin 1 - A recently discovered human longevity enzyme that extends lifespan by reducing inflammation and enhancing DNA repair enzymes. Acti-Sirtuin appears to mimic the same longevity gene that calorie restriction has on the human body. Acti-Sirtuin also inhibits telomerase, the harmful enzyme responsible for shortening the end caps (telomeres) of chromosomes. Over the course of your life-time, as telomere length decreases so does the number of times a cell can replicate. Acti-Sirtuin helps to maintain telomere length and therefore helps prolong cellular life. This amazing compound is also believed to be responsible for the French Paradox where by the French have the highest intake of saturated fat and the lowest incidence of heart disease.

Extracted from the seeds of non-GMO soybeans grown in the US, CardiAid™ Phytosterols (including β-Sitosterol, Campesterol, Stigmasterol) found in NuvoCELL™ support healthy immune function by preventing cholesterol oxidation and the associated inflammation and immune system dysfunction this causes. Inflammation is the root cause of all disease and disorder and phytosterols inhibit that absorption and metabolism of cholesterol helping to naturally protect the vascular system, heart and cellular DNA from inflammation and free-radical production.

Derived from authentic Indian Coleus Forskholii Root, FORSLEAN™ Colforsin is a safe breakthrough new phytocompound that significantly reduces body fat levels, prevents loss of muscle and firms up the appearance of skin. This compound works synergisticallly with the other two compounds in NuvoFIT™ to naturally stimulate adenylate cyclase and cyclic AMP levels. This is the key driver that activates hormone sensitive lipase (HSL) which causes the breakdown and release of stored body fat.

A pharmaceutically manufactured source of Ultra-High Purity™ caffeine, this compound positively influences the body's fat mass to lean mass ratio by promoting fat oxidation and increases thermogenesis wihtout over stimulating the central nervous system. This compound contributes to the ability of NuvoFIT™ to break down and metabolize fat efficiently helping to support an improvement in lean body composition.

Pro-Carnosine™ Beta-alanine has been included in NuvoFIT™ to prevent muscle loss and support lean body composition. Several clinical studies have investigated the effects of beta-alanine on muscle physiology, strength and performance. Research has proved that supplementation with beta-alanine results in a significant increase in muscle carnosine levels and help to prevent loss of muscle tissue. Further more, because Beta-Alanine is a precursor to carnosine, it helps prevent the formation of cell damaging Advanced Glycation End Products (AGE) in the body. AGE promotes pre-mature ageing and is known to speed up the human ageing process.

Derived from astaREAL™ Hawaiian Deep Red Microalgae, Astaxanthin sits atop the antioxidant pyramid! A new study recently published demonstrated Astaxanthin to be 1000 times more effective than vitamin E (-tocopherol), and 15 times stronger than Vitamin C, Vitamin E, and beta-carotene in combating singlet oxygen species (SOS) free-radicals. Singlet Oxygen Species is the most dangerous free-radical in the body that Directly damages the epidermal layer of the skin and destroys healthy cellular function. Astaxanthin was even shown to be stronger than Alpha Lipoic Acid and Co-Enzyme Q10. AstaREAL® is the highest quality source of natural astaxanthincommercially available and is grown and is cultivated in Hawaii utlizing a patented and proprietary fully enclosed biosystems, resulting in a product that has the highest level of purity.

Derived from authentic Chinese Green Tea Leaf grown in the soils of Tibet, Epigallocatechin-Gallate (EGCG) is the key thearapeutic phytocompound extracted from the green tea leaf. Environmental pollutants and UV light are two of the key factors that contribute to skin damage resulting in appearance of fine lines and wrinkles. Research indicates the polyphenol content in green tea protects the skin from UV damage from the sun. EGCG has been identified as the most potent and most important photoprotective (skin protecting) polyphenolic component in green tea. In research conducted at the Medical College of Georgia (Depar™ent of Oral Biology), Dr. Stephen Hsu found that EGCG reactivated dying skin cells. "Cells that migrate toward the surface of the skin normally live about 28 days, and by day 20, they basically sit on the upper layer of the skin getting ready to die," Dr. Hsu said. "But EGCG reactivates them. I was so surprised." Interesting to note is EGCG is at least 100 more times more effective than vitamin C and 25 times more effective than vitamin E at protecting cells and DNA.

Derived from authentic Siberian Golden Root, Rosavins and Salidrosides have been collectively shown to reduce stress and anxiety while promoting a clean, stress-free feeling of energy and well being. Stress is a major contributor to poor skin health. Acting as a next-generation adaptogenic compound (Ginseng is considered a first-generation), the phytocompounds in Siberian Golden Root increase resistance to stress. Furthermore, subjects receiving the exact level of Rosavins and Salidrosides found in AGEOFF® decreased mental fatigue and situational anxiety during stressful periods. Ultimately by controlling stress, you can suppress Cortisol and the inflammation helping to control skin inflammation and puffiness.

Vitamin C is required for the growth and repair of tissues in all parts of your body and is considered to be one of the most powerful biological antioxidants. Vitamin C is one of the most important nutrients involved in the formation of collagen, the most important protein used to make new healthy skin cells. The NHPD has approved the use of vitamin C as an antioxidant for the maintenance of good health.

New research into the preventive benefits of vitamin D has raised hopes that the sunshine vitamin, which is produced naturally in the body through exposure to the sun's ultraviolet rays, could extend and improve people's lives. In September 2007, an analysis of 18 randomized controlled trials involving people over the age of 50 found that people who took at least 500 international units (IU) of vitamin D daily had a seven per cent lower risk of death compared with those given a placebo. AGEOFF provide 800IU per daily dosage and is a key vitamin in AGEOFF®.

Vitamin E is a fat soluble antioxidant that helps to improve the health and appearance of skin, and also promote DNA repair. The antioxidant properties of vitamin E help combat oxidative stress and help maintain the integrity of DNA at the cellular level by neutralizing .

Vitamin B3 is vital for energy release in tissues and cells, as it helps form the coenzymes NAD (nicotinamide adenine dinucleotide) and NADP (nicotinamide adenine dinucleotide phosphate), which are involved in the release of energy from food.

Vitamin B6 is required for proper synthesis of DNA in the human body thus supporting the DNA repair process. Vitamin B6 also aids in the production of neurotransmitters, the chemicals that allow brain and nerve cells to communicate with one another. Vi™ain B6 also ensure metabolic processing of fat and protein metabolism run smoothly. This nutrient is also important for immune system function in older individuals.

Folic acid works along with vitamin B12, Vitamin B6 and Vitamin C to increase DNA synthesis. The vitamin helps form red blood cells and helps produce DNA, the building block of the human body, which carries genetic information. Previous studies at Harvard concluded that 400 micrograms of folate, together with vitamin B6, taken daily, cuts the risk of heart disease by a third. AGEOFF® provides 400 mcg of folic acid per daily dosage!

Vitamin B12's primary function is the formation of red blood cells and the maintenance of a healthy nervous system by supporting the protective sheath that encases the nerves. B12 is also essential in the rapid synthesis of DNA during cell division.

Zinc is critical to the entire body's immune and repair processes. When skin is injured, the site of injury becomes saturated with zinc within 90 minutes. As we age and the health of the skin declines it becomes critical to provide the aged skin cells with adequate levels of Zinc for proper repair and skin rejuvenation. The inability of elderly people to heal quickly or heal completely is most frequently related to inadequate zinc levels. Zinc has been added to the AGEOFF formula to ensure adequate zinc levels are delivered on a daily basis.

Selenium is an essential component of the bodies most powerful internally produced antioxidant - glutathione peroxidase. Results of two 5-year-long studies at Cornell University and the University of Arizona revealed that taking supplementary selenium each day cut the incidence of cancer and the death rate from cancer was found to be 39% lower than that of the general population.